A woman runs for cover during clashes in Port Said in Egypt on Thursday (Photo: Khalil Hamra/AP)
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Police said they fired shots into the air to disperse a crowd of stone-throwing demonstrators.
Ezz al-Din al-Dawla is the second Iraqi minister to announce his resignation over the handling of mainly-Sunni protests, staged daily against the al-Maliki Government since December.
"I announce my resignation before the Iraqi people and my people in Mosul because there is no way to continue any longer with a government that does not respond to my people's demands," said Dawla, a member of the Sunni-backed Iraqiyya Bloc, in a televised news conference.
Minister of Finance Rafa al-Issawi, whose home and offices were raided by security forces in December, quit earlier this month.
Thousands of protesters took to the streets again in the cities of Mosul, Samarra, and Kirkuk and in Anbar Province on Friday. They again demanded the release of detainees and the scrapping of anti-terrorism laws they say are unfairly used against them.